Matthew Mifsud, MD

Surgical Oncology, Head and Neck Surgical Oncology, Otolaryngology
Matthew Mifsud image
4.8 out of 5
361 ratings, 42 comments
2 Tampa General Circle, Tampa, FL 33606
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Office Number
813-821-8012
Fax Number
813-821-9702
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Online Booking
As a head and neck surgical oncologist, my major focus is the treatment within the head and neck region, affecting the face, neck, mouth and throat. At USF, I help lead a multidisciplinary team of medical professionals, that develop individualized cancer treatment plans, for each of our patients.





I have extensive surgical training and experience, which includes advanced subspecialization within my field of otolaryngology. This allows me to perform a wide array of surgical procedures and particularly focus on reconstructive surgery. This entails taking body parts from one area and transplanting them into the head and neck. This helps maintain a more normal physical appearance and optimizes speech/swallowing function, which can be impacted by cancer or other maladies. I'm able to not only treat a person's disease, but also help to optimize their quality of life long after treatment is complete.





In addition to cancer, I also focus on other complex head and neck conditions, such as those affecting the salivary glands, thyroid, and trachea. At USF, I also engage in various teaching and research activities, which enhance my ability to provide state-of-the-art care to all my patients.


About Matthew

Patient Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.
4.8 out of 5
361 ratings,
42 reviews
9/26/2025
Dr Mifsud is very compassionate, he listened to my concerns, he treated me with respect. I am happy that he is my doctor
9/24/2025
Excellent experience
9/23/2025
Dr Mifsud is very compassionate, and listened to my concerns. He treated me with respect and friendship
9/21/2025
Great experience
9/18/2025
I appreciate the time she took to answer my questions fur our visit.

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Map & Directions

USF Health Department of Otolaryngology - Head and Neck Surgery

2 Tampa General CircleTampa, FL 33606
Monday - Friday

8:00 am - 5:00 pm

Saturday - Sunday

Closed

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